Our Inter-Array<\/a> division offers spotting services, e.g. for multi-parameter assays. <\/p>\n\n In the mylab system solutions<\/a> division, you will find measuring devices for quality control, e.g. in the production of foodstuffs, as well as services and products in the fields of environmental analysis or laboratory and point-of-care diagnostics.<\/p>\n\n The veterinary clinic <\/a>at our institute treats large and small animals in almost all medical areas. In addition to the small animal practice, our veterinary clinic focuses in particular on the medical care of horses.<\/p>\n\n Microarrays consist of a large number of microscopic spots that can be precisely deposited on a solid surface by high-precision dispensers. For example, more than 700 spots can be applied in a single well of a 96-well microtiter plate.<\/p>\n <\/p>\n Customized development<\/strong><\/p>\n In the business unit INTER-ARRAY<\/a> at the fzmb we accompany you through all development phases of microarrays from feasibility studies to pilot production. After successful development, we are available to you as a contract manufacturing partner<\/em> with our ISO-certified production capacities.<\/p>\n <\/p>\n Microarray quality control<\/b><\/p>\n The focus is on the high quality of the microarray products. For production, the dispensing systems operate in a climate-controlled environment with inline QC software, ensuring quality control of all arrays produced.<\/p>\n <\/strong><\/p>\n <\/p>\n <\/p>\n Information<\/strong><\/p>\n For more information, visit our website at www.inter-array.com<\/a>.<\/p>\n <\/p>\n <\/p>\n Contact<\/strong><\/p>\n Katrin Frankenfeld<\/p>\n Head of Biotechnology Department<\/p>\n phone +49 3603 – 833 141<\/p>\n Email kfrankenfeld@fzmb.de<\/a><\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n<\/div> Protein and antibody microarray technology offers enormous potential for a wide range of diagnostic applications. Miniaturized, parallelized immunoassays as well as DNA-based microarrays are ideal for generating maximum diagnostically relevant information with small sample and reagent volumes. A microarray thus saves a lot of time, valuable samples and expensive raw material.<\/p>\n <\/p>\n Application in human and veterinary medicine<\/b><\/p>\n The use of microarrays in human and veterinary diagnostics is of interest for all applications where multiple analytes can be determined from a single sample.<\/p>\n Typical examples of multiparameter analysis are allergy and food intolerance tests, the diagnosis of autoimmune, metabolic and infectious diseases, and cancer diagnostics. The technology offers excellent prospects for new ways of individualized diagnostics and personalized medicine.<\/p>\n <\/p>\n Multi-parameter analysis in different formats<\/b><\/b><\/p>\n In the business area <\/span>INTER-ARRAY<\/a> <\/span>at the fzmb we carry out new developments of various multiparameter tests. Standard detection formats such as ELISA, lateral flow strips, and microfluidic assays can be used, as well as custom platforms.<\/p>\n Our team offers flexible support for feasibility, validation as well as production projects for various microarray based assays. In addition to completely new development, the transfer of existing tests to the microarray platform is also possible.<\/p>\n <\/p>\n Information<\/strong><\/p>\n For more information, visit our website at www.inter-array.com<\/a>.<\/p>\n <\/p>\n <\/p>\n Contact<\/strong><\/p>\n Katrin Frankenfeld<\/p>\n Head of Biotechnology Department<\/p>\n phone +49 3603 – 833 141<\/p>\n Email kfrankenfeld@fzmb.de<\/a><\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n<\/div> In order to apply very small volumes of capture molecules (from picoliters to microliters) to any surface with high precision, a lot of experience is required in addition to very good dispensing systems. Our INTER-ARRAY<\/a> business unit at fzmb is equipped with a wide range of state-of-the-art microdispensers and has many years of specialist know-how.<\/p>\n <\/p>\n With our established technologies for high-precision dispensing and our years of experience from design to data analysis, we create an exclusive printing offering in the life science sector. We offer this all-round service at an attractive price\/performance ratio. The focus is on high quality and short production times.<\/p>\n <\/p>\n Spotting of various substances<\/strong><\/p>\n Substances that can be spotted include antibodies, other proteins and peptides, oligonucleotides, carbohydrates, cells and cell lysates, particles and chemical compounds, and special customer-supplied molecules. Substrates to be coated include glass and polymer slides, microtiter plates and microcavities, membranes and microfluidic chips, wafers, biosensors, and customized surfaces.<\/p>\n <\/p>\n Information<\/strong><\/p>\n For more information, visit our website at www.inter-array.com<\/a>.<\/p>\n <\/p>\n <\/p>\n Contact<\/strong><\/p>\n Katrin Frankenfeld<\/p>\n Head of Biotechnology Department<\/p>\n phone +49 3603 – 833 141<\/p>\n Email kfrankenfeld@fzmb.de<\/a><\/p>\n<\/div> The lateral flow assay (LFA) is an immunological strip test. It combines the principle of thin-layer chromatography<\/a> with antibody-based detection (colorimetric, enzymatic or fluorescence). An LFA is the basis for cost-effective, highly sensitive and reliable detection of a wide range of analytes.<\/p>\n As a point-of-care test (POCT), lateral flow assays find multiple applications e.g. in immunodiagnostics or in the analysis of environmental and food samples.<\/p>\n The ELISA(enzyme-linked immunosorbent assay<\/a>) is used for the qualitative and\/or quantitative detection of an analyte (antigen) in a sample. In addition, many samples can be analyzed in parallel and automated in a laboratory environment.<\/p>\n We develop LFAs and ELISAs from feasibility to small-scale production or preparation for large-scale production. These immunoassays can be used to diagnostically detect a wide variety of analytes in complex sample matrices. Highly specific and affine monoclonal and polyclonal antibodies are required for reliable selective binding of the analyte in a liquid phase or tissue sample. Their production and application-related characterization is one of our core competencies.<\/p>\n <\/p>\n Reliable detection of biological structures with high sensitivity<\/strong><\/p>\n Imunoassays can detect the analytes of interest down to the nanogram range, in some cases even the picogram range. Qualitative and quantitative detection is possible from a wide variety of biological samples with complex compositions without pretreatment.<\/p>\n At fzmb, rapid highly specific test systems with colorimetric, fluorescence or chemiluminescence-based readout for any parameter are developed.<\/p>\n <\/p>\n Performance overview<\/strong><\/p>\n <\/p>\n <\/strong><\/p>\n Contact<\/strong><\/p>\n Email diagnostik@fzmb.de<\/a><\/p>\n<\/div> The lateral flow assay (LFA) is an immunological strip test. It combines the principle of thin-layer chromatography with antibody-based detection.<\/p>\n At fzmb, we develop LFAs from feasibility to small-scale production or preparation for large-scale production.<\/p>\n <\/p>\n More information from a quick test<\/strong><\/p>\n Is it covid-19, RSV, or influenza (A or B)? If more than one question arises the answer should be sufficient, too We have therefore developed a new platform for lateral flow assays. On this new platform, up to 6 different tests can be integrated in one run (6in1 combinatied rapid tests).<\/p>\n <\/p>\n Use of special nanoparticles<\/strong><\/p>\n We use special fluorescent nanoparticles as a basis, which we conjugate with the corresponding antibodies. Thus, we achieve not only multiplexing (several tests combined). The sensitivity (detection limit of the respective analyte) is improved by up to 10 times.<\/p>\n <\/p>\n <\/p>\n The readout of the combination tests is done digitally with an appropriate readout device. Two variants are available for this purpose: For laboratory applications, commercially available devices (lateral flow fluorescence readers) can be used. In cooperation, we also offer solutions ready for series production for home use.<\/p>\n <\/strong><\/p>\n <\/p>\n Contact<\/strong><\/p>\n Email diagnostik@fzmb.de<\/a><\/p>\n <\/p>\n<\/div> <\/div>\n<\/section>\n\n Monoclonal antibodies can be generated for almost any antigen or epitope. These are the basis for various immunological-based detection methods, such as diagnostic ELISA tests. Unlike polyclonal antibodies, monoclonal antibodies are only produced by one cell clone (monoclonal) and therefore bind highly specifically to the epitope of the desired target structure. <\/p>\n <\/p>\n We use the mouse host organism to develop monoclonal antibodies. The antibodies are generated using hybridoma technology, i.e. the fusion of spleen cells and myeloma cells. <\/p>\n For rapid downstream development, we immediately offer antibody characterization and matched-pair analysis. This identifies the pairings of detector and capture antibodies that are best suited to your desired test system. <\/p>\n <\/p>\n In addition to the production of antibodies, we also produce antigens. The antigens can be recombinant and native proteins, peptides or microorganisms and can be used, for example, to develop specific antibodies. <\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n email diagnostik@fzmb.de<\/a><\/p>\n <\/p>\n <\/p>\n monoclonal antibodies directed against<\/strong><\/p>\n <\/p>\n Contact<\/strong><\/p>\n Email diagnostik@fzmb.de<\/a><\/p>\n<\/div> In human medicine, so-called chimeric (about 75 % human) and humanized antibodies have been used for more than 20 years. There are now a large number of approved therapeutic antibodies for human use. As a company with strong ties to veterinary medicine, our mission is to develop novel immunological therapies for companion animals.<\/p>\n <\/strong><\/p>\n Specific antibodies for therapy <\/strong><\/p>\n We are developing recombinant equine-specific antibodies for subsequent therapeutic use in horses. The current focus is the development of an antibody against matrix metalloproteinase 9 (MMP-9). This antibody is intended to serve as a specific therapeutic agent, for example, for the targeted treatment of arthritis, wound healing disorders and equine sarcoid. But also in other diseases in which an overexpression of matrix metalloproteinase 9 (MMP-9) is causally involved, a new therapeutic option is to be created. In this way, pathological processes that arise due to the tissue-degrading properties of MMP-9 can be specifically stopped at the site of their development.<\/p>\n <\/p>\n recombinant equine immunoglobulins<\/strong><\/p>\n Molecular genetic methods have been developed for the production of equine recombinant antibodies in cell culture. Furthermore, these techniques can be used to produce other equine immunoglobulins, for example, as passive immunotherapeutics against equine infectious diseases. Based on the choice of subtype specificity and the regulatory Fc region, beyond the desired antigen specificity, the potential as a modulator can be used to strengthen the body’s immune system, e.g. against an existing cancer.<\/p>\n Go with us conversation about your concern and issue. Our ambition is to work with you to lay the foundations for innovative and specific immunotherapy for the horse.<\/p>\n If we have aroused your interest, please feel free to contact us.<\/p>\n Contact<\/strong><\/p>\n Dr. Ina-Gabriele Richter<\/p>\n phone +49 3603 – 833 177<\/p>\n Email irichter@fzmb.de<\/a><\/p>\n<\/div> We produce artificial human immune sera by means of in-vitro immunization.<\/p>\n <\/p>\n Contact<\/strong><\/p>\n Dr. Ina-Gabriele Richter<\/p>\n phone +49 3603 – 833 177<\/p>\n Email irichter@fzmb.de<\/a><\/p>\n<\/div> Whether a chosen matched-pair antibody works well in a planned application depends on many factors and cannot be predicted.<\/p>\n We therefore not only offer the development of specific monoclonal antibodies (including the identification of matched pairs) for e.g. Immunoassay developments on.<\/p>\n For best performance of a Matched Antibody Pair, we test the performance of these antibody pairs in the desired application. This early testing of antibodies in the target application (ELISA, LFA with immunogold or fluorescent nanoparticles, IFAT) enables targeted antibody selection or development and thus allows the best possible performance.<\/p>\n <\/p>\n Performance overview<\/strong><\/p>\n <\/p>\n Contact<\/strong><\/p>\n Email: diagnostik@fzmb.de<\/a><\/p>\n <\/p>\n <\/p>\n<\/div> <\/div>\n<\/section>\n\n The testing laboratory in the food testing department<\/a> at the fzmb has been an independent service provider for food safety and consumer protection since 1994. The laboratory is accredited by the German Accreditation Body (DAkkS) in accordance with DIN EN ISO 17025.<\/p>\n <\/p>\n Food Microbiology<\/strong><\/p>\n <\/p>\n Industrial hygiene<\/strong><\/p>\n <\/p>\n Food Chemistry<\/strong><\/p>\n <\/p>\n chemical-physical<\/strong><\/p>\n <\/p>\n Drinking water<\/strong><\/p>\n <\/p>\n concrete problems in the following areas:<\/p>\n <\/p>\n PDF List of test methods<\/strong> in the food testing department<\/a><\/p>\n <\/p>\n <\/p>\n <\/p>\n Contact<\/strong><\/p>\n Steffi Leuschke<\/p>\n State-certified food chemist<\/p>\n phone +49 3603 – 833 173<\/p>\nDiagnostic systems <\/h2>\n <\/header>\n
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<\/div>\n <\/div>\n Development and production of microarrays<\/strong><\/h4>\n
Development and production of multiparameter tests<\/strong><\/h4>\n
High precision dispensing <\/strong><\/h4>\n
From design to data analysis: Exclusive printing offers<\/strong><\/h4>\n
Immunoassay development<\/strong><\/h4>\n
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Highly sensitive 4in1\/ 6in1 antigen rapid tests<\/strong><\/h4>\n
![\"Graphic](\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2023\/07\/bild3d2d_v2l2_li-300x157.png\")
<\/p>\n![\"Graphic](\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2023\/07\/Grafik-Nanopartikel-AK-konjugiert-150x150.png\")
<\/p>\nPDF Highly sensitive combination rapid tests<\/strong>
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<\/a><\/p>\nSpecific antibodies<\/h2>\n <\/header>\n
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<\/div>\n <\/div>\n Production of monoclonal antibodies<\/h4>\n
Application-related characterization of monoclonal antibodies<\/h4>\n
Also production of antigens<\/h4>\n
The most important advantages at a glance<\/h4>\n
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Performance overview<\/strong><\/h4>\n
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Contact<\/h4>\n
Overview of monoclonal antibody-producing cell lines at the fzmb<\/h4>\n
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Production of recombinant antibodies (horse)<\/h4>\n
Production of polyclonal antibodies<\/h4>\n
Matched Pair Antibodies<\/h4>\n
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Analysis of food, drinking water and cosmetics<\/h2>\n <\/header>\n
![\"Foto](\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2023\/03\/drop-of-water-g544da2f17_1920.jpg\")
<\/div>\n <\/div>\n Laboratory for food testing<\/h4>\n
Which products do we analyze?<\/h4>\n
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What services do we offer?<\/h4>\n
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other services<\/h4>\n
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