{"id":4255,"date":"2025-08-07T10:01:01","date_gmt":"2025-08-07T08:01:01","guid":{"rendered":"https:\/\/www.fzmb.de\/next-generation-sequencing\/"},"modified":"2025-08-11T16:04:50","modified_gmt":"2025-08-11T14:04:50","slug":"next-generation-sequencing","status":"publish","type":"page","link":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/","title":{"rendered":"Next Generation Sequencing"},"content":{"rendered":"\n
\n

Next Generation Sequencing (NGS) is a modern technology that enables rapid genetic testing. <\/p>\n\n\n\n

Using NGS, millions of DNA or RNA fragments can be analyzed in parallel and evaluated with correspondingly powerful bioinformatics tools. <\/p>\n\n\n\n

NGS is used, for example, in the diagnosis of cancer, infections or to analyze the intestinal flora (microbiome) in humans and other mammals.<\/p>\n<\/div>

\"\"<\/figure><\/div>\n\n
\n
\n

NGS: our strengths<\/h2>\n\n\n\n

Flexibility<\/strong>. Predefined analysis path (standard) or customer-specific application with maximum output. <\/p>\n\n\n\n

Technology<\/strong>. State-of-the-art tools (QIAGEN panels, 10x genomics). <\/p>\n\n\n\n

Reproducibility<\/strong>. Standardized workflows with nf-core\/Nextflow. <\/p>\n\n\n\n

Efficiency<\/strong>. Resource-saving methods (Salmon, BIAS correction). <\/p>\n\n\n\n

Comprehensive<\/strong>. From QC to interactive visualizations. <\/p>\n<\/div>\n\n\n\n

<\/div>\n\n\n\n
\n

our NGS expertise<\/h2>\n\n\n\n

Our five-member NGS team combines expertise in molecular and microbiology, bioinformatics and data analysis.<\/p>\n\n\n\n

We thus serve both other research partners and industrial applications with resource-saving and reproducible analyses.<\/p>\n\n\n\n

<\/div>\n\n\n\n

NGS special applications<\/h2>\n\n\n\n

– DNA metabarcoding for food analysis– project-specific amplicon-based analyses– industrial microbiome characterization– comprehensive research support <\/p>\n<\/div>\n<\/div>\n\n

<\/div>\n\n
\n
\n
\n
<\/path><\/path><\/svg><\/span>

NGS analysis of your samples (full service)<\/h2><\/div>
<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n
\n
\n
\n
<\/path><\/path><\/svg><\/span>

NGS analysis of your data<\/h2><\/div>
\n

Our technology stack<\/h2>\n\n\n\n

<\/p>\n\n\n\n

We rely on state-of-the-art bioinformatics tools and pipelines, e.g. <\/p>\n\n\n\n

QIIME2<\/strong> for microbiome analyses<\/p>\n\n\n\n

nf-core<\/strong> for standardized pipelines<\/p>\n\n\n\n

Nextflow<\/strong> for workflow management<\/p>\n\n\n\n

Seurat<\/strong> for single cell analysis<\/p>\n\n\n\n

DESeq2 & edgeR<\/strong> for differential expression studies<\/p>\n\n\n\n

Salmon<\/strong> for Alignment & Quantification<\/p>\n\n\n\n

cellranger<\/strong> for 10x genomics processing<\/p>\n\n\n\n

FastQC & fastp<\/strong> for quality control<\/p>\n\n\n\n

DAVID & EnrichR<\/strong> for GO Enrichment<\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n

\n
\n
\n
<\/path><\/path><\/svg><\/span>

Package solutions<\/h2><\/div>
<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n
<\/div>\n\n
\n
\n
\n

Full Service Next Generation Sequencing <\/h2>\n <\/header>\n
\n
\n
Microbiome analysis, 16s and ITS analysis<\/div> <\/div>\n
\n \"\" <\/div>\n <\/div>\n
\n

Microbiome analysis, 16s and ITS analysis<\/h3>\n

Professional amplicon-based microbiome analyses with state-of-the-art methods and individual customization.<\/p>\n

    \n
  • Analysis of all variable regions in the 16S rRNA gene<\/li>\n
  • QIAGEN 16S\/ITS Screening Panel<\/li>\n
  • Specific regions (e.g. V3\/V4)<\/li>\n
  • ITS evaluation (fungal profiling, forward reads)<\/li>\n
  • Taxonomic identification up to genus level<\/li>\n
  • Alpha\/beta diversity & differential abundance<\/li>\n
  • DNA metabarcoding (meat, fish, shellfish)<\/li>\n
  • Interactive visualizations & reports<\/li>\n<\/ul>\n<\/div> <\/div>\n<\/section><\/div>\n<\/div>\n\n
    <\/div>\n\n
    \n
    \n
    \n

    Bioinformatics services (evaluations)<\/h2>\n <\/header>\n
    \n
    \n
    Standard analysis (fast & inexpensive)<\/div>
    Individual analytics (max. output)<\/div> <\/div>\n
    \n \"\" <\/div>\n <\/div>\n
    \n
    <\/div>
    <\/div> <\/div>\n<\/section><\/div>\n<\/div>\n\n
    <\/div>\n\n

    Your contact for information and offers<\/h2>\n\n
    \n

    Dr. Ina-Gabriele Richter<\/strong><\/p>\n\n\n\n

    EMail: irichter@fzmb.de<\/p>\n\n\n\n

    Phone: + 49 36038 833-177<\/p>\n<\/div>

    \"Photo<\/figure><\/div>\n\n

    <\/p>\n","protected":false},"excerpt":{"rendered":"

    Next Generation Sequencing (NGS) is a modern technology that enables rapid genetic testing. Using NGS, millions of DNA or RNA fragments can be analyzed in parallel and evaluated with correspondingly powerful bioinformatics tools. NGS is used, for example, in the diagnosis of cancer, infections or to analyze the intestinal flora (microbiome) in humans and other […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"class_list":["post-4255","page","type-page","status-publish","hentry"],"yoast_head":"\nNext Generation Sequencing - fzmb GmbH - Research Center for Medical Technology and Biotechnology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Next Generation Sequencing\" \/>\n<meta property=\"og:description\" content=\"Next Generation Sequencing (NGS) is a modern technology that enables rapid genetic testing. Using NGS, millions of DNA or RNA fragments can be analyzed in parallel and evaluated with correspondingly powerful bioinformatics tools. NGS is used, for example, in the diagnosis of cancer, infections or to analyze the intestinal flora (microbiome) in humans and other […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/\" \/>\n<meta property=\"og:site_name\" content=\"fzmb GmbH - Research Center for Medical Technology and Biotechnology\" \/>\n<meta property=\"article:modified_time\" content=\"2025-08-11T14:04:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/\",\"url\":\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/\",\"name\":\"Next Generation Sequencing - fzmb GmbH - Research Center for Medical Technology and Biotechnology\",\"isPartOf\":{\"@id\":\"https:\/\/www.fzmb.de\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg\",\"datePublished\":\"2025-08-07T08:01:01+00:00\",\"dateModified\":\"2025-08-11T14:04:50+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#primaryimage\",\"url\":\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg\",\"contentUrl\":\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\/\/www.fzmb.de\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Next Generation Sequencing\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.fzmb.de\/en\/#website\",\"url\":\"https:\/\/www.fzmb.de\/en\/\",\"name\":\"fzmb GmbH - Forschungszentrum f\u00fcr Medizintechnik und Biotechnologie\",\"description\":\"Founding member of the Zuse community and the FTVT\",\"publisher\":{\"@id\":\"https:\/\/www.fzmb.de\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.fzmb.de\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.fzmb.de\/en\/#organization\",\"name\":\"fzmb GmbH - Forschungszentrum f\u00fcr Medizintechnik und Biotechnologie\",\"url\":\"https:\/\/www.fzmb.de\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.fzmb.de\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/fzmb_Logo.svg\",\"contentUrl\":\"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/fzmb_Logo.svg\",\"caption\":\"fzmb GmbH - Forschungszentrum f\u00fcr Medizintechnik und Biotechnologie\"},\"image\":{\"@id\":\"https:\/\/www.fzmb.de\/en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.youtube.com\/@fzmbgmbh2951\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Next Generation Sequencing - fzmb GmbH - Research Center for Medical Technology and Biotechnology","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/","og_locale":"en_US","og_type":"article","og_title":"Next Generation Sequencing","og_description":"Next Generation Sequencing (NGS) is a modern technology that enables rapid genetic testing. Using NGS, millions of DNA or RNA fragments can be analyzed in parallel and evaluated with correspondingly powerful bioinformatics tools. NGS is used, for example, in the diagnosis of cancer, infections or to analyze the intestinal flora (microbiome) in humans and other […]","og_url":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/","og_site_name":"fzmb GmbH - Research Center for Medical Technology and Biotechnology","article_modified_time":"2025-08-11T14:04:50+00:00","og_image":[{"url":"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/","url":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/","name":"Next Generation Sequencing - fzmb GmbH - Research Center for Medical Technology and Biotechnology","isPartOf":{"@id":"https:\/\/www.fzmb.de\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#primaryimage"},"image":{"@id":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#primaryimage"},"thumbnailUrl":"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg","datePublished":"2025-08-07T08:01:01+00:00","dateModified":"2025-08-11T14:04:50+00:00","breadcrumb":{"@id":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#primaryimage","url":"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg","contentUrl":"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/HomeContent_forschung-1024x531.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.fzmb.de\/en\/next-generation-sequencing\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/www.fzmb.de\/en\/"},{"@type":"ListItem","position":2,"name":"Next Generation Sequencing"}]},{"@type":"WebSite","@id":"https:\/\/www.fzmb.de\/en\/#website","url":"https:\/\/www.fzmb.de\/en\/","name":"fzmb GmbH - Forschungszentrum f\u00fcr Medizintechnik und Biotechnologie","description":"Founding member of the Zuse community and the FTVT","publisher":{"@id":"https:\/\/www.fzmb.de\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.fzmb.de\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.fzmb.de\/en\/#organization","name":"fzmb GmbH - Forschungszentrum f\u00fcr Medizintechnik und Biotechnologie","url":"https:\/\/www.fzmb.de\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.fzmb.de\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/fzmb_Logo.svg","contentUrl":"https:\/\/www.fzmb.de\/wp-content\/uploads\/2022\/09\/fzmb_Logo.svg","caption":"fzmb GmbH - Forschungszentrum f\u00fcr Medizintechnik und Biotechnologie"},"image":{"@id":"https:\/\/www.fzmb.de\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.youtube.com\/@fzmbgmbh2951"]}]}},"acf":[],"coauthors":[],"author_meta":{"author_link":"https:\/\/www.fzmb.de\/en\/author\/heise\/","display_name":"heise"},"relative_dates":{"created":"Posted 11 months ago","modified":"Updated 11 months ago"},"absolute_dates":{"created":"Posted on 7. August 2025","modified":"Updated on 11. August 2025"},"absolute_dates_time":{"created":"Posted on 7. August 2025 10:01","modified":"Updated on 11. August 2025 16:04"},"featured_img_caption":"","featured_img":false,"series_order":"","_links":{"self":[{"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/pages\/4255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/comments?post=4255"}],"version-history":[{"count":49,"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/pages\/4255\/revisions"}],"predecessor-version":[{"id":4414,"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/pages\/4255\/revisions\/4414"}],"wp:attachment":[{"href":"https:\/\/www.fzmb.de\/en\/wp-json\/wp\/v2\/media?parent=4255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}