Next Generation Sequencing (NGS) is a modern technology that enables rapid genetic testing.
Using NGS, millions of DNA or RNA fragments can be analyzed in parallel and evaluated with correspondingly powerful bioinformatics tools.
NGS is used, for example, in the diagnosis of cancer, infections or to analyze the intestinal flora (microbiome) in humans and other mammals.
NGS: our strengths
Flexibility. Predefined analysis path (standard) or customer-specific application with maximum output.
Technology. State-of-the-art tools (QIAGEN panels, 10x genomics).
Reproducibility. Standardized workflows with nf-core/Nextflow.
Efficiency. Resource-saving methods (Salmon, BIAS correction).
Comprehensive. From QC to interactive visualizations.
our NGS expertise
Our five-member NGS team combines expertise in molecular and microbiology, bioinformatics and data analysis.
We thus serve both other research partners and industrial applications with resource-saving and reproducible analyses.
NGS special applications
– DNA metabarcoding for food analysis
– project-specific amplicon-based analyses
– industrial microbiome characterization
– comprehensive research support
NGS analysis of your samples (full service)
NGS analysis of your data
Package solutions
Full Service Next Generation Sequencing
Microbiome analysis, 16s and ITS analysis
Professional amplicon-based microbiome analyses with state-of-the-art methods and individual customization.
- Analysis of all variable regions in the 16S rRNA gene
- QIAGEN 16S/ITS Screening Panel
- Specific regions (e.g. V3/V4)
- ITS evaluation (fungal profiling, forward reads)
- Taxonomic identification up to genus level
- Alpha/beta diversity & differential abundance
- DNA metabarcoding (meat, fish, shellfish)
- Interactive visualizations & reports
Bulk RNA sequencing
State-of-the-art transcriptome analyses with bias-corrected, resource-saving methods.
- Quality control (FastQC, fastp)
- Resource-friendly alignment (Salmon + Decoy)
- BIAS correction (GC-, position-, sequence-BIAS)
- Differential expression (DESeq2, edgeR)
- Gene Ontology Enrichment (DAVID, EnrichR)
- Visualizations (heat maps, PCA, Top 50 DEGs)
- Excel export & comprehensive reports
High-resolution single cell analysis with 10x Genomics Chromium and professional workflows.
- 10x Genomics Chromium Technology
- Quality control (FastQC)
- Preprocessing (cellranger)
- Clustering & marker identification
- Downstream analyses (Seurat, Loupe Browser)
- Visualizations (UMAP, t-SNE, violin and elbow plots)
- Differential expression at gene level
- Comprehensive tables & reports
Bioinformatics services (evaluations)
