Our focus is on applied research for human and animal health. We are specialized in the development of new diagnostic detection methods and new analytical methods. We are also developing new therapies for animal health.
We link our competences in the fields of cell biology, in vitro diagnostics, biotechnology and optical analytics internally with applications of our veterinary clinic, externally with needs of large and small companies. Our food testing laboratory also creates the interface for healthy food.
As a business-oriented research institution in the Zuse community, we are the link between science and industry. Our application-oriented research and development of processes and products thus enables rapid implementation in the market.
current investments in research
Structure Platform Next Generation Sequencing
The COVID-19 pandemic highlighted the need for a rapid response to the emergence of new, pathogenic agents and/or pathogen variants.
At fzmb, we want to meet this challenge. In order to identify and characterize new pathogens (variants) more quickly, we are establishing a next generation sequencing platform. Using this high-throughput method, we can visualize even the smallest genetic changes (such as mutations) in a short time. On this basis, we can subsequently develop improved/adapted diagnostics such as rapid tests (lateral flow assays) for self-testing or ELISAs/microarraries for laboratory diagnostics.
The project, which is supported by the Free State of Thuringia, is co-financed by funds from the European Union within the framework of the REACT-EU Fund. The realization was carried out after a limited invitation to tender without a competition in accordance with ThürVVöA as a sub-threshold supply service. For this purpose, an NG sequencer from Illumina and the necessary computing hardware from Godyo GmbH were purchased. An FPLC (Äkta pure 25 M) from Cytiva was purchased for sample preparation and separation. For quality control, a TapeStation from Agilent), for DNA quantification a Qubit from Thermo Fisher Scientific and for a PCR cycler (TAdvanced from Analytik Jena) were procured. An Arpege170 cryogenic container was purchased through VWR for sample storage.
Expansion of the “Highly Specific Antibodies” technology platform
The emergence of new, pathogenic agents and/or pathogen variants requires rapid responses. We are taking up this challenge and investing in the development of specific antibodies for new pathogens. On this basis, we can subsequently develop, for example, improved/adapted diagnostics such as rapid tests.
The following equipment was procured for the expansion of the “Highly Specific Antibodies” technology platform at the fzmb: An electrofusion and electroporation generator (Fisher Scientific GmbH, Schwerte) was procured for the preparation of cells for transfection. For the selection and characterization of antibody-producing cells, a fluorescence microscope (Thunder Imager 3D Assay, Leica Mikrosysteme GmbH, Wetzlar, Germany) including components and accessories, a microscope stage with accessories (Thorlabs GmbH, Beikirchen, Germany) and the corresponding air purification system (KKT Kratochwill GmbH, Mühlhausen, Germany) were procured. The project, which is supported by the Free State of Thuringia, is co-financed by funds from the European Union within the framework of the REACT-EU Fund. The realization was carried out after a limited invitation to tender without a competition in accordance with ThürVVöA as a sub-threshold supply service.
current promotions in the consultation
Innovation voucher for the establishment of a new R&D collaboration
Immunotherapies use the body’s own immune system to effectively fight inflammatory processes or cancer, for example. The “Preparation of an R&D cooperation project for the development of an immunotherapy for specific bone diseases” project funded by the Free State of Thuringia is co-financed by funds from the European Union. The objectives of the innovation assistance include preliminary studies, intensive research on the status of these diseases and their current therapeutic options, market analyses, etc.
Entrepreneurial accompaniment – Subsidy according to consulting guideline
The fzmb GmbH is not only a research institute but also acts as a medium-sized company. In order to cooperate even more successfully with partners in foreign markets, we use intensive consulting and process support by independent management consultants. This project is supported by RKW Thüringen GmbH.